HIV Target gene Detail Information

> ARFGAP3 Gene Search Result

Gene Information

Gene Name	ARFGAP3
Gene ID	26286
Gene Full Name	ADP ribosylation factor GTPase activating protein 3
Gene Alias	ARFGAP1
Transcripts	ENSG00000242247
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Golgi apparatus;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NP61
HGNC ID	HGNC:661
VEGA ID	OTTHUMG00000150718
OMIM ID	612439
String ID	9606.ENSP00000263245
PharmGKB ID	PA35024

Target gene [ARFGAP3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003302	chr22	59		5	64	View
4006052	chr22	12	10	5	27	View
4010380	chr22	5	4		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARFGAP3 expression and immune infiltrating cell level correlation result in HIV+ samples
ARFGAP3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARFGAP3 expression and immune infiltrating cell level correlation result in HIV+ samples
ARFGAP3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).