HIV Target gene Detail Information

> ARF4 Gene Search Result


Gene Information
Gene Name ARF4
Gene ID 378
Gene Full Name ADP ribosylation factor 4
Gene Alias ARF2
Transcripts ENSG00000168374
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P18085
HGNC ID HGNC:655
VEGA ID OTTHUMG00000158601
OMIM ID 601177
String ID 9606.ENSP00000306010
Drugbank ID BE0003277
PharmGKB ID PA24937
Target gene [ARF4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004241 chr3 10 27 10 47 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ARF4 expression and immune infiltrating cell level correlation result in HIV+ samples
ARF4 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ARF4 expression and immune infiltrating cell level correlation result in HIV+ samples
ARF4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).