HIV Target gene Detail Information

> ARCN1 Gene Search Result

Gene Information

Gene Name	ARCN1
Gene ID	372
Gene Full Name	archain 1
Gene Alias	COPD; SRMMD
Transcripts	ENSG00000095139
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;Cytosol;Golgi apparatus;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P48444
HGNC ID	HGNC:649
VEGA ID	OTTHUMG00000166340
OMIM ID	600820
String ID	9606.ENSP00000264028
PharmGKB ID	PA24931

Target gene [ARCN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001468	chr11	49	46	66	161	View
4001485	chr11	48	45	66	159	View
4007312	chr11	12	6	2	20	View
4011560	chr11		1	5	6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARCN1 expression and immune infiltrating cell level correlation result in HIV+ samples
ARCN1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARCN1 expression and immune infiltrating cell level correlation result in HIV+ samples
ARCN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).