HIV Target gene Detail Information

> ARAP2 Gene Search Result


Gene Information
Gene Name ARAP2
Gene ID 116984
Gene Full Name ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Gene Alias PARX; CENTD1
Transcripts ENSG00000047365
Virus HIV
Gene Type protein coding
HPA Location Info Focal adhesion sites;Actin filaments;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8WZ64
HGNC ID HGNC:16924
VEGA ID OTTHUMG00000097811
OMIM ID 606645
String ID 9606.ENSP00000302895
PharmGKB ID PA164715938
Target gene [ARAP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001437 chr4 159 4 2 165 View
4002713 chr4 22 61 83 View
4007737 chr4 18 18 View
4014956 chr4 1 1 View
4014957 chr4 1 1 View
4015542 chr4 1 1 View
4300005 chr4 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ARAP2 expression and immune infiltrating cell level correlation result in HIV+ samples
ARAP2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).