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HBV Target gene Detail Information

> APPL2 Gene Search Result


Gene Information
Gene Name APPL2
Gene ID 55198
Gene Full Name adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
Gene Alias DIP13B
Transcripts ENSG00000136044
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q8NEU8
HGNC ID HGNC:18242
VEGA ID OTTHUMG00000169853
OMIM ID 606231
String ID 9606.ENSP00000446917
PharmGKB ID PA164741199
Target gene [APPL2] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
1014134 chr12 4 4 View
Showing 1 to 1 of 1 entries
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of APPL2 expression and immune infiltrating cell level correlation result in HBV+ samples
APPL2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).