HBV Target gene Detail Information

> APOL3 Gene Search Result


Gene Information
Gene Name APOL3
Gene ID 80833
Gene Full Name apolipoprotein L3
Gene Alias CG121; CG12_1; APOLIII; apoL-III
Transcripts ENSG00000128284
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O95236
HGNC ID HGNC:14868
VEGA ID OTTHUMG00000150632
OMIM ID 607253
String ID 9606.ENSP00000344577
PharmGKB ID PA24906
Target gene [APOL3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005702 chr22 26 23 49 View
1005771 chr22 25 23 48 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of APOL3 expression and immune infiltrating cell level correlation result in HBV+ samples
APOL3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).