HBV Target gene Detail Information

> APOL2 Gene Search Result

Gene Information

Gene Name	APOL2
Gene ID	23780
Gene Full Name	apolipoprotein L2
Gene Alias	APOL3; APOL-II
Transcripts	ENSG00000128335
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9BQE5
HGNC ID	HGNC:619
VEGA ID	OTTHUMG00000150634
OMIM ID	607252
String ID	9606.ENSP00000249066
PharmGKB ID	PA24905

Target gene [APOL2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004040	chr22	80	14	2	96	View
1004041	chr22	80	14	2	96	View
1004042	chr22	80	14	2	96	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of APOL2 expression and immune infiltrating cell level correlation result in HBV+ samples
APOL2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).