HBV Target gene Detail Information

> APOB Gene Search Result

Gene Information

Gene Name	APOB
Gene ID	338
Gene Full Name	apolipoprotein B
Gene Alias	FLDB; LDLCQ4; apoB-48; apoB-100
Transcripts	ENSG00000084674
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;Predicted to be secreted;
HPA Protein Class Info	Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID	P04114
HGNC ID	HGNC:603
VEGA ID	OTTHUMG00000090785
OMIM ID	107730
String ID	9606.ENSP00000233242
Drugbank ID	BE0010251; BE0009908
PharmGKB ID	PA50

Target gene [APOB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007004	chr2	14	6	11	31	View
1015436	chr2	2			2	View
1400064	chr2	28			28	View
1400065	chr2	6		1	7	View
1404154	chr2	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of APOB expression and immune infiltrating cell level correlation result in HBV+ samples
APOB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).