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HBV Target gene Detail Information

> APOA1 Gene Search Result


Gene Information
Gene Name APOA1
Gene ID 335
Gene Full Name apolipoprotein A1
Gene Alias apo(a)
Transcripts ENSG00000118137
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Cytosol;Predicted to be secreted;
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P02647
HGNC ID HGNC:600
VEGA ID OTTHUMG00000046112
OMIM ID 107680
String ID 9606.ENSP00000236850
Drugbank ID BE0003449
PharmGKB ID PA49
Target gene [APOA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000179 chr11 2671 1113 1001 4785 View
1005474 chr11 43 11 54 View
1006802 chr11 31 2 1 34 View
1006803 chr11 31 2 1 34 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of APOA1 expression and immune infiltrating cell level correlation result in HBV+ samples
APOA1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).