HBV Target gene Detail Information

> APLNR Gene Search Result

Gene Information

Gene Name	APLNR
Gene ID	187
Gene Full Name	apelin receptor
Gene Alias	APJ; APJR; HG11; AGTRL1
Transcripts	ENSG00000134817
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted membrane proteins, Transporters
Uniport_ID	P35414
HGNC ID	HGNC:339
VEGA ID	OTTHUMG00000167021
OMIM ID	600052
String ID	9606.ENSP00000475344
PharmGKB ID	PA162376687

Target gene [APLNR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010054	chr11	13			13	View
1401259	chr11	13			13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of APLNR expression and immune infiltrating cell level correlation result in HBV+ samples
APLNR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).