HIV Target gene Detail Information

> APEH Gene Search Result

Gene Information

Gene Name	APEH
Gene ID	327
Gene Full Name	acylaminoacyl-peptide hydrolase
Gene Alias	APH; OPH; AARE; ACPH; D3S48E; D3F15S2; DNF15S2
Transcripts	ENSG00000164062
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P13798
HGNC ID	HGNC:586
VEGA ID	OTTHUMG00000156882
OMIM ID	102645
String ID	9606.ENSP00000296456
PharmGKB ID	PA24878

Target gene [APEH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003613	chr3	44	9	5	58	View
4007571	chr3	18	1		19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of APEH expression and immune infiltrating cell level correlation result in HIV+ samples
APEH expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of APEH expression and immune infiltrating cell level correlation result in HIV+ samples
APEH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).