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HPV Target gene Detail Information

> APCS Gene Search Result


Gene Information
Gene Name APCS
Gene ID 325
Gene Full Name amyloid P component, serum
Gene Alias SAP; PTX2; HEL-S-92n
Transcripts ENSG00000132703
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters
Uniport_ID P02743
HGNC ID HGNC:584
VEGA ID OTTHUMG00000022741
OMIM ID 104770
String ID 9606.ENSP00000255040
Drugbank ID BE0001213
PharmGKB ID PA24877
Target gene [APCS] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5404719 chr1 1 3 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of APCS expression and immune infiltrating cell level correlation result in HPV+ samples
APCS expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of APCS expression and immune infiltrating cell level correlation result in HPV+ samples
APCS expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of APCS expression and immune infiltrating cell level correlation result in HPV+ samples
APCS expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of APCS expression and immune infiltrating cell level correlation result in HPV+ samples
APCS expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of APCS expression and immune infiltrating cell level correlation result in HPV+ samples
APCS expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of APCS expression and immune infiltrating cell level correlation result in HPV+ samples
APCS expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).