HBV Target gene Detail Information

> APC Gene Search Result

Gene Information

Gene Name	APC
Gene ID	324
Gene Full Name	APC, WNT signaling pathway regulator
Gene Alias	GS; DP2; DP3; BTPS2; DP2.5; PPP1R46
Transcripts	ENSG00000134982
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Golgi apparatus;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P25054
HGNC ID	HGNC:583
VEGA ID	OTTHUMG00000128806
OMIM ID	611731
String ID	9606.ENSP00000257430
PharmGKB ID	PA24875

Target gene [APC] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010635	chr5		11		11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of APC expression and immune infiltrating cell level correlation result in HBV+ samples
APC expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).