HIV Target gene Detail Information

> APBB1IP Gene Search Result

Gene Information

Gene Name	APBB1IP
Gene ID	54518
Gene Full Name	amyloid beta precursor protein binding family B member 1 interacting protein
Gene Alias	RIAM; INAG1; PREL1; RARP1
Transcripts	ENSG00000077420
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q7Z5R6
HGNC ID	HGNC:17379
VEGA ID	OTTHUMG00000017841
OMIM ID	609036
String ID	9606.ENSP00000365411
PharmGKB ID	PA134933955

Target gene [APBB1IP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002017	chr10	105	12		117	View
4009198	chr10	11	1		12	View
4013837	chr10	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of APBB1IP expression and immune infiltrating cell level correlation result in HIV+ samples
APBB1IP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of APBB1IP expression and immune infiltrating cell level correlation result in HIV+ samples
APBB1IP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).