HBV Target gene Detail Information

> APBA2 Gene Search Result


Gene Information
Gene Name APBA2
Gene ID 321
Gene Full Name amyloid beta precursor protein binding family A member 2
Gene Alias X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091
Transcripts ENSG00000276495
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q99767
HGNC ID HGNC:579
VEGA ID OTTHUMG00000191387
OMIM ID 602712
String ID 9606.ENSP00000453293
PharmGKB ID PA24870
Target gene [APBA2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006991 chr15 26 3 2 31 View
1011665 chr15 8 8 View
1013569 chr15 4 1 5 View
1402054 chr15 26 3 2 31 View
1404257 chr15 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of APBA2 expression and immune infiltrating cell level correlation result in HBV+ samples
APBA2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).