HBV Target gene Detail Information

> APBA1 Gene Search Result


Gene Information
Gene Name APBA1
Gene ID 320
Gene Full Name amyloid beta precursor protein binding family A member 1
Gene Alias X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA
Transcripts ENSG00000276497
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q02410
HGNC ID HGNC:578
VEGA ID OTTHUMG00000175384
OMIM ID 602414
String ID 9606.ENSP00000265381
PharmGKB ID PA24869
Target gene [APBA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001570 chr9 147 157 306 610 View
1004787 chr9 9 51 9 69 View
1007998 chr9 13 4 6 23 View
1010012 chr9 13 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of APBA1 expression and immune infiltrating cell level correlation result in HBV+ samples
APBA1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).