HIV Target gene Detail Information

> AP4E1 Gene Search Result

Gene Information

Gene Name	AP4E1
Gene ID	23431
Gene Full Name	adaptor related protein complex 4 subunit epsilon 1
Gene Alias	CPSQ4; SPG51; STUT1
Transcripts	ENSG00000081014
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9UPM8
HGNC ID	HGNC:573
VEGA ID	OTTHUMG00000172458
OMIM ID	607244
String ID	9606.ENSP00000261842
PharmGKB ID	PA24865

Target gene [AP4E1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003951	chr15	41	11		52	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AP4E1 expression and immune infiltrating cell level correlation result in HIV+ samples
AP4E1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of AP4E1 expression and immune infiltrating cell level correlation result in HIV+ samples
AP4E1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).