HIV Target gene Detail Information

> AP3D1 Gene Search Result

Gene Information

Gene Name	AP3D1
Gene ID	8943
Gene Full Name	adaptor related protein complex 3 subunit delta 1
Gene Alias	ADTD; HPS10; hBLVR
Transcripts	ENSG00000065000
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	O14617
HGNC ID	HGNC:568
VEGA ID	OTTHUMG00000180354
OMIM ID	607246
String ID	9606.ENSP00000347416
PharmGKB ID	PA24859

Target gene [AP3D1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002095	chr19	108	2	2	112	View
4005998	chr19	15	13		28	View
4006080	chr19	24	3		27	View
4008902	chr19	12	1		13	View
4009458	chr19	9	2		11	View
4012091	chr19	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AP3D1 expression and immune infiltrating cell level correlation result in HIV+ samples
AP3D1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of AP3D1 expression and immune infiltrating cell level correlation result in HIV+ samples
AP3D1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).