HPV Target gene Detail Information

> AP3B2 Gene Search Result

Gene Information

Gene Name	AP3B2
Gene ID	8120
Gene Full Name	adaptor related protein complex 3 subunit beta 2
Gene Alias	NAPTB; EIEE48
Transcripts	ENSG00000103723
Virus	HPV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q13367
HGNC ID	HGNC:567
VEGA ID	OTTHUMG00000168009
OMIM ID	602166
String ID	9606.ENSP00000440984
PharmGKB ID	PA24858

Target gene [AP3B2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402215	chr15	6	1		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of AP3B2 expression and immune infiltrating cell level correlation result in HPV+ samples
AP3B2 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of AP3B2 expression and immune infiltrating cell level correlation result in HPV+ samples
AP3B2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).