HIV Target gene Detail Information

> AP2A1 Gene Search Result

Gene Information

Gene Name	AP2A1
Gene ID	160
Gene Full Name	adaptor related protein complex 2 subunit alpha 1
Gene Alias	ADTAA; CLAPA1; AP2-ALPHA
Transcripts	ENSG00000196961
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O95782
HGNC ID	HGNC:561
VEGA ID	OTTHUMG00000183253
OMIM ID	601026
String ID	9606.ENSP00000351926
PharmGKB ID	PA24852

Target gene [AP2A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005704	chr19	2	19	9	30	View
4010049	chr19		10		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AP2A1 expression and immune infiltrating cell level correlation result in HIV+ samples
AP2A1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of AP2A1 expression and immune infiltrating cell level correlation result in HIV+ samples
AP2A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).