HBV Target gene Detail Information

> ANXA3 Gene Search Result

Gene Information

Gene Name	ANXA3
Gene ID	306
Gene Full Name	annexin A3
Gene Alias	ANX3
Transcripts	ENSG00000138772
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P12429
HGNC ID	HGNC:541
VEGA ID	OTTHUMG00000130198
OMIM ID	106490
String ID	9606.ENSP00000264908
Drugbank ID	BE0003201
PharmGKB ID	PA24831

Target gene [ANXA3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007743	chr4	22	3		25	View
1404337	chr4	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ANXA3 expression and immune infiltrating cell level correlation result in HBV+ samples
ANXA3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).