HIV Target gene Detail Information

> ANXA2 Gene Search Result

Gene Information

Gene Name	ANXA2
Gene ID	302
Gene Full Name	annexin A2
Gene Alias	P36; ANX2; LIP2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV; HEL-S-270
Transcripts	ENSG00000182718
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;Predicted to be secreted;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters
Uniport_ID	P07355
HGNC ID	HGNC:537
VEGA ID	OTTHUMG00000132763
OMIM ID	151740
String ID	9606.ENSP00000346032
Drugbank ID	BE0001170
PharmGKB ID	PA24827

Target gene [ANXA2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005931	chr15	10	18		28	View
4006819	chr15	12	10		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ANXA2 expression and immune infiltrating cell level correlation result in HIV+ samples
ANXA2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ANXA2 expression and immune infiltrating cell level correlation result in HIV+ samples
ANXA2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).