HIV Target gene Detail Information

> ANO8 Gene Search Result

Gene Information

Gene Name	ANO8
Gene ID	57719
Gene Full Name	anoctamin 8
Gene Alias	TMEM16H; KIAA1623
Transcripts	ENSG00000074855
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9HCE9
HGNC ID	HGNC:29329
VEGA ID	OTTHUMG00000182665
OMIM ID	610216
String ID	9606.ENSP00000159087
PharmGKB ID	PA164715790

Target gene [ANO8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003390	chr19	29	33		62	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ANO8 expression and immune infiltrating cell level correlation result in HIV+ samples
ANO8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ANO8 expression and immune infiltrating cell level correlation result in HIV+ samples
ANO8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).