HBV Target gene Detail Information

> ANO4 Gene Search Result

Gene Information

Gene Name	ANO4
Gene ID	121601
Gene Full Name	anoctamin 4
Gene Alias	TMEM16D
Transcripts	ENSG00000262139
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q32M45
HGNC ID	HGNC:23837
VEGA ID	OTTHUMG00000174894
OMIM ID	610111
String ID	9606.ENSP00000376703
PharmGKB ID	PA164715582

Target gene [ANO4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005088	chr12	30	13	18	61	View
1019481	chr12				0	View
1401176	chr12	30	13	18	61	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ANO4 expression and immune infiltrating cell level correlation result in HBV+ samples
ANO4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).