HBV Target gene Detail Information

> ANO2 Gene Search Result

Gene Information

Gene Name	ANO2
Gene ID	57101
Gene Full Name	anoctamin 2
Gene Alias	C12orf3; TMEM16B
Transcripts	ENSG00000047617
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9NQ90
HGNC ID	HGNC:1183
VEGA ID	OTTHUMG00000168264
OMIM ID	610109
String ID	9606.ENSP00000348453
PharmGKB ID	PA25504

Target gene [ANO2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009039	chr12	18			18	View
1010723	chr12	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ANO2 expression and immune infiltrating cell level correlation result in HBV+ samples
ANO2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).