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HBV Target gene Detail Information

> ANO1 Gene Search Result


Gene Information
Gene Name ANO1
Gene ID 55107
Gene Full Name anoctamin 1
Gene Alias DOG1; TAOS2; ORAOV2; TMEM16A
Transcripts ENSG00000131620
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID Q5XXA6
HGNC ID HGNC:21625
VEGA ID OTTHUMG00000167204
OMIM ID 610108
String ID 9606.ENSP00000347454
Drugbank ID BE0004746
PharmGKB ID PA164715378
Target gene [ANO1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005060 chr11 45 17 62 View
1007888 chr11 19 4 23 View
1011648 chr11 5 2 1 8 View
1015054 chr11 3 3 View
1401260 chr11 45 17 62 View
1401261 chr11 5 2 1 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ANO1 expression and immune infiltrating cell level correlation result in HBV+ samples
ANO1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).