HTLV1 Target gene Detail Information

> ANKRD54 Gene Search Result


Gene Information
Gene Name ANKRD54
Gene ID 129138
Gene Full Name ankyrin repeat domain 54
Gene Alias LIAR
Transcripts ENSG00000100124
Virus HTLV1
Gene Type protein coding
HPA Location Info Microtubules;Midbody;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q6NXT1
HGNC ID HGNC:25185
VEGA ID OTTHUMG00000150663
OMIM ID 613383
String ID 9606.ENSP00000215941
PharmGKB ID PA145149843
Target gene [ANKRD54] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001597 chr22 384 5 389 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ANKRD54 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ANKRD54 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ANKRD54 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ANKRD54 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).