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HBV Target gene Detail Information

> ANKRD11 Gene Search Result


Gene Information
Gene Name ANKRD11
Gene ID 29123
Gene Full Name ankyrin repeat domain 11
Gene Alias T13; LZ16; ANCO1; ANCO-1
Transcripts ENSG00000167522
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q6UB99
HGNC ID HGNC:21316
VEGA ID OTTHUMG00000175548
OMIM ID 611192
String ID 9606.ENSP00000301030
PharmGKB ID PA134861925
Target gene [ANKRD11] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005575 chr16 14 11 26 51 View
1008007 chr16 18 5 23 View
1400378 chr16 6 6 View
1403671 chr16 14 11 26 51 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ANKRD11 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ANKRD11 expression: Low -> High
Lollipop of ANKRD11 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ANKRD11 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ANKRD11 expression and immune infiltrating cell level correlation result in HBV+ samples
ANKRD11 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).