HIV Target gene Detail Information

> ANKFY1 Gene Search Result

Gene Information

Gene Name	ANKFY1
Gene ID	51479
Gene Full Name	ankyrin repeat and FYVE domain containing 1
Gene Alias	ANKHZN; BTBD23; ZFYVE14
Transcripts	ENSG00000185722
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endosomes;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9P2R3
HGNC ID	HGNC:20763
VEGA ID	OTTHUMG00000177727
OMIM ID	607927
String ID	9606.ENSP00000459943
PharmGKB ID	PA134984226

Target gene [ANKFY1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000226	chr17	439	67	190	696	View
4000507	chr17	135	75	203	413	View
4004472	chr17	43			43	View
4009619	chr17	8	2	1	11	View
4012535	chr17	5			5	View
4016757	chr17				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ANKFY1 expression and immune infiltrating cell level correlation result in HIV+ samples
ANKFY1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ANKFY1 expression and immune infiltrating cell level correlation result in HIV+ samples
ANKFY1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).