HBV Target gene Detail Information

> ANK3 Gene Search Result

Gene Information

Gene Name	ANK3
Gene ID	288
Gene Full Name	ankyrin 3
Gene Alias	MRT37; ANKYRIN-G
Transcripts	ENSG00000151150
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q12955
HGNC ID	HGNC:494
VEGA ID	OTTHUMG00000018288
OMIM ID	600465
String ID	9606.ENSP00000280772
PharmGKB ID	PA24800

Target gene [ANK3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011492	chr10	6	3		9	View
1011760	chr10	6	2		8	View
1011920	chr10	5	3		8	View
1012499	chr10	5	1		6	View
1015575	chr10	2			2	View
1016014	chr10	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ANK3 expression and immune infiltrating cell level correlation result in HBV+ samples
ANK3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).