HBV Target gene Detail Information

> ANK2 Gene Search Result

Gene Information

Gene Name	ANK2
Gene ID	287
Gene Full Name	ankyrin 2
Gene Alias	LQT4; ANK-2; brank-2
Transcripts	ENSG00000145362
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	Q01484
HGNC ID	HGNC:493
VEGA ID	OTTHUMG00000132912
OMIM ID	106410
String ID	9606.ENSP00000349588
PharmGKB ID	PA24799

Target gene [ANK2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001218	chr11	237	286	378	901	View
1005486	chr11	45	8		53	View
1007755	chr11	14	6	4	24	View
1008899	chr11	16	2		18	View
1010740	chr11	10	1		11	View
1011828	chr11	5		3	8	View
1012865	chr4	6			6	View
1403510	chr11	16	2		18	View
1403632	chr11	45	8		53	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ANK2 expression and immune infiltrating cell level correlation result in HBV+ samples
ANK2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).