HBV Target gene Detail Information

> ANK1 Gene Search Result


Gene Information
Gene Name ANK1
Gene ID 286
Gene Full Name ankyrin 1
Gene Alias ANK; SPH1; SPH2
Transcripts ENSG00000029534
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID P16157
HGNC ID HGNC:492
VEGA ID OTTHUMG00000150281
OMIM ID 612641
String ID 9606.ENSP00000265709
PharmGKB ID PA24798
Target gene [ANK1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000630 chr10 766 383 592 1741 View
1002041 chr4 140 176 49 365 View
1003002 chr10 171 4 3 178 View
1006129 chr9 41 2 43 View
1007650 chr8 20 4 24 View
1011070 chr8 9 1 10 View
1016001 chr20 1 1 2 View
1016033 chr20 1 1 2 View
1016037 chr20 1 1 2 View
1016041 chr20 1 1 2 View
1016049 chr20 1 1 2 View
1016054 chr20 1 1 2 View
1016055 chr20 1 1 2 View
1016065 chr20 1 1 2 View
1019421 chr10 0 View
1401031 chr4 140 176 49 365 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ANK1 expression and immune infiltrating cell level correlation result in HBV+ samples
ANK1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).