HTLV1 Target gene Detail Information

> ANG Gene Search Result

Gene Information

Gene Name	ANG
Gene ID	283
Gene Full Name	angiogenin
Gene Alias	ALS9; RAA1; HEL168; RNASE4; RNASE5
Transcripts	ENSG00000214274
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitotic chromosome;Nucleoli;Nucleoli rim;Actin filaments;Predicted to be secreted;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID	P03950
HGNC ID	HGNC:483
VEGA ID	OTTHUMG00000029576
OMIM ID	105850
String ID	9606.ENSP00000336762
Drugbank ID	BE0001181
PharmGKB ID	PA24790

Target gene [ANG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000775	chr14	295	337	233	865	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ANG expression and immune infiltrating cell level correlation result in HTLV1+ samples
ANG expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ANG expression and immune infiltrating cell level correlation result in HTLV1+ samples
ANG expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ANG expression and immune infiltrating cell level correlation result in HTLV1+ samples
ANG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).