HIV Target gene Detail Information

> AMBRA1 Gene Search Result

Gene Information

Gene Name	AMBRA1
Gene ID	55626
Gene Full Name	autophagy and beclin 1 regulator 1
Gene Alias	DCAF3; WDR94
Transcripts	ENSG00000110497
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9C0C7
HGNC ID	HGNC:25990
VEGA ID	OTTHUMG00000166500
OMIM ID	611359
String ID	9606.ENSP00000431926
PharmGKB ID	PA162376307

Target gene [AMBRA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002575	chr11	7	55	26	88	View
4003861	chr11	46	7		53	View
4009516	chr11	10	1		11	View
4010819	chr11	7	1		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AMBRA1 expression and immune infiltrating cell level correlation result in HIV+ samples
AMBRA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).