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HBV Target gene Detail Information

> AMBP Gene Search Result


Gene Information
Gene Name AMBP
Gene ID 259
Gene Full Name alpha-1-microglobulin/bikunin precursor
Gene Alias A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
Transcripts ENSG00000106927
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Cytosol;Golgi apparatus;Predicted to be secreted;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P02760
HGNC ID HGNC:453
VEGA ID OTTHUMG00000020534
OMIM ID 176870
String ID 9606.ENSP00000265132
PharmGKB ID PA24759
Target gene [AMBP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003446 chr9 34 94 5 133 View
1007508 chr9 21 5 1 27 View
1007511 chr9 25 2 27 View
1007604 chr9 20 5 1 26 View
1015098 chr9 3 3 View
1400074 chr2 3 1 4 View
1400148 chr9 78 27 18 123 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of AMBP expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
AMBP expression: Low -> High
Lollipop of AMBP expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of AMBP expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of AMBP expression and immune infiltrating cell level correlation result in HBV+ samples
AMBP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).