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HPV Target gene Detail Information

> ALX4 Gene Search Result


Gene Information
Gene Name ALX4
Gene ID 60529
Gene Full Name ALX homeobox 4
Gene Alias CRS5; FND2
Transcripts ENSG00000052850
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q9H161
HGNC ID HGNC:450
VEGA ID OTTHUMG00000166557
OMIM ID 605420
String ID 9606.ENSP00000332744
PharmGKB ID PA24755
Target gene [ALX4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5201565 chr11 50 1 51 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of ALX4 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX4 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of ALX4 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX4 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of ALX4 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX4 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of ALX4 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX4 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of ALX4 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX4 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of ALX4 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX4 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).