HPV Target gene Detail Information

> ALX1 Gene Search Result


Gene Information
Gene Name ALX1
Gene ID 8092
Gene Full Name ALX homeobox 1
Gene Alias FND3; CART1; HEL23
Transcripts ENSG00000180318
Virus HPV
Gene Type protein coding
HPA Location Info Nuclear bodies;Golgi apparatus;Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q15699
HGNC ID HGNC:1494
VEGA ID OTTHUMG00000169820
OMIM ID 601527
String ID 9606.ENSP00000315417
PharmGKB ID PA162376294
Target gene [ALX1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5404812 chr12 12 4 1 17 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of ALX1 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX1 expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of ALX1 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX1 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of ALX1 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX1 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of ALX1 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX1 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of ALX1 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX1 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of ALX1 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX1 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of ALX1 expression and immune infiltrating cell level correlation result in HPV+ samples
ALX1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).