HBV Target gene Detail Information

> ALS2 Gene Search Result

Gene Information

Gene Name	ALS2
Gene ID	57679
Gene Full Name	ALS2, alsin Rho guanine nucleotide exchange factor
Gene Alias	ALSJ; PLSJ; IAHSP; ALS2CR6
Transcripts	ENSG00000003393
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Intermediate filaments;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q96Q42
HGNC ID	HGNC:443
VEGA ID	OTTHUMG00000154507
OMIM ID	606352
String ID	9606.ENSP00000264276
PharmGKB ID	PA24732

Target gene [ALS2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009552	chr2	8	7		15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ALS2 expression and immune infiltrating cell level correlation result in HBV+ samples
ALS2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).