HBV Target gene Detail Information

> ALPI Gene Search Result


Gene Information
Gene Name ALPI
Gene ID 248
Gene Full Name alkaline phosphatase, intestinal
Gene Alias IAP
Transcripts ENSG00000163295
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID P09923
HGNC ID HGNC:437
VEGA ID OTTHUMG00000133258
OMIM ID 171740
String ID 9606.ENSP00000295463
Drugbank ID BE0008299
PharmGKB ID PA24728
Target gene [ALPI] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007240 chr2 29 29 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ALPI expression and immune infiltrating cell level correlation result in HBV+ samples
ALPI expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).