Home
Virus
Gene
Disease
Dataset
Download
Help
 
HPV Target gene Detail Information

> ALOX5AP Gene Search Result


Gene Information
Gene Name ALOX5AP
Gene ID 241
Gene Full Name arachidonate 5-lipoxygenase activating protein
Gene Alias FLAP
Transcripts ENSG00000132965
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted membrane proteins
Uniport_ID P20292
HGNC ID HGNC:436
VEGA ID OTTHUMG00000016677
OMIM ID 603700
String ID 9606.ENSP00000479870
Drugbank ID BE0002382
PharmGKB ID PA47
Target gene [ALOX5AP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5401574 chr13 2 1 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of ALOX5AP expression and immune infiltrating cell level correlation result in HPV+ samples
ALOX5AP expression: Low -> High

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of ALOX5AP expression and immune infiltrating cell level correlation result in HPV+ samples
ALOX5AP expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of ALOX5AP expression and immune infiltrating cell level correlation result in HPV+ samples
ALOX5AP expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of ALOX5AP expression and immune infiltrating cell level correlation result in HPV+ samples
ALOX5AP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).