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HBV Target gene Detail Information

> ALMS1 Gene Search Result


Gene Information
Gene Name ALMS1
Gene ID 7840
Gene Full Name ALMS1, centrosome and basal body associated protein
Gene Alias ALSS
Transcripts ENSG00000116127
Virus HBV
Gene Type protein coding
HPA Location Info Centrosome;Cytosol;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
HGNC ID HGNC:428
VEGA ID OTTHUMG00000152812
OMIM ID 606844
String ID 9606.ENSP00000482968
PharmGKB ID PA24721
Target gene [ALMS1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015802 chr2 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of ALMS1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
ALMS1 expression: Low -> High
Lollipop of ALMS1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of ALMS1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ALMS1 expression and immune infiltrating cell level correlation result in HBV+ samples
ALMS1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).