HIV Target gene Detail Information

> ALKBH8 Gene Search Result

Gene Information

Gene Name	ALKBH8
Gene ID	91801
Gene Full Name	alkB homolog 8, tRNA methyltransferase
Gene Alias	ABH8; TRM9; TRMT9; TRMT9A
Transcripts	ENSG00000137760
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q96BT7
HGNC ID	HGNC:25189
VEGA ID	OTTHUMG00000157008
OMIM ID	613306
String ID	9606.ENSP00000397673
PharmGKB ID	PA143485296

Target gene [ALKBH8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004267	chr19	47			47	View
4005352	chr11	32	1		33	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ALKBH8 expression and immune infiltrating cell level correlation result in HIV+ samples
ALKBH8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).