HIV Target gene Detail Information

> ALG6 Gene Search Result


Gene Information
Gene Name ALG6
Gene ID 29929
Gene Full Name ALG6, alpha-1,3-glucosyltransferase
Gene Alias CDG1C
Transcripts ENSG00000088035
Virus HIV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID Q9Y672
HGNC ID HGNC:23157
VEGA ID OTTHUMG00000009140
OMIM ID 604566
String ID 9606.ENSP00000360149
PharmGKB ID PA134925619
Target gene [ALG6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004136 chr1 46 2 48 View
4007645 chr1 16 2 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ALG6 expression and immune infiltrating cell level correlation result in HIV+ samples
ALG6 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ALG6 expression and immune infiltrating cell level correlation result in HIV+ samples
ALG6 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).