HIV Target gene Detail Information

> ALG12 Gene Search Result

Gene Information

Gene Name	ALG12
Gene ID	79087
Gene Full Name	ALG12, alpha-1,6-mannosyltransferase
Gene Alias	CDG1G; ECM39; hALG12; PP14673
Transcripts	ENSG00000182858
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID	Q9BV10
HGNC ID	HGNC:19358
VEGA ID	OTTHUMG00000150289
OMIM ID	607144
String ID	9606.ENSP00000333813
PharmGKB ID	PA134987771

Target gene [ALG12] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002130	chr22	108	3		111	View
4007787	chr22	16	2		18	View
4007788	chr22	16	2		18	View
4007789	chr22	16	2		18	View
4008025	chr22	17			17	View
4008026	chr22	17			17	View
4010244	chr22	7	2		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ALG12 expression and immune infiltrating cell level correlation result in HIV+ samples
ALG12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).