HBV Target gene Detail Information

> ALDH1L1 Gene Search Result


Gene Information
Gene Name ALDH1L1
Gene ID 10840
Gene Full Name aldehyde dehydrogenase 1 family member L1
Gene Alias FDH; FTHFD; 10-fTHF; 10-FTHFDH
Transcripts ENSG00000144908
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID O75891
HGNC ID HGNC:3978
VEGA ID OTTHUMG00000125551
OMIM ID 600249
String ID 9606.ENSP00000273450
Drugbank ID BE0000933
PharmGKB ID PA28393
Target gene [ALDH1L1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006887 chr3 31 2 33 View
1009002 chr3 18 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ALDH1L1 expression and immune infiltrating cell level correlation result in HBV+ samples
ALDH1L1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).