HBV Target gene Detail Information

> ALDH1A1 Gene Search Result


Gene Information
Gene Name ALDH1A1
Gene ID 216
Gene Full Name aldehyde dehydrogenase 1 family member A1
Gene Alias ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e
Transcripts ENSG00000165092
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID P00352
HGNC ID HGNC:402
VEGA ID OTTHUMG00000020019
OMIM ID 100640
String ID 9606.ENSP00000297785
Drugbank ID BE0000554
PharmGKB ID PA24692
Target gene [ALDH1A1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009000 chr9 15 1 2 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ALDH1A1 expression and immune infiltrating cell level correlation result in HBV+ samples
ALDH1A1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).