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HTLV1 Target gene Detail Information

> ALDH18A1 Gene Search Result


Gene Information
Gene Name ALDH18A1
Gene ID 5832
Gene Full Name aldehyde dehydrogenase 18 family member A1
Gene Alias GSAS; P5CS; PYCS; SPG9; ADCL3; SPG9A; SPG9B; ARCL3A
Transcripts ENSG00000059573
Virus HTLV1
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P54886
HGNC ID HGNC:9722
VEGA ID OTTHUMG00000018815
OMIM ID 138250
String ID 9606.ENSP00000360268
Drugbank ID BE0000823
PharmGKB ID PA34065
Target gene [ALDH18A1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6012825 chr10 21 21 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ALDH18A1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ALDH18A1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of ALDH18A1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ALDH18A1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ALDH18A1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ALDH18A1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).