Home
Virus
Gene
Disease
Dataset
Download
Help
 
HIV Target gene Detail Information

> AKT3 Gene Search Result


Gene Information
Gene Name AKT3
Gene ID 10000
Gene Full Name AKT serine/threonine kinase 3
Gene Alias MPPH; PKBG; MPPH2; PRKBG; STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma
Transcripts ENSG00000275199
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID Q9Y243
HGNC ID HGNC:393
VEGA ID OTTHUMG00000189637
OMIM ID 611223
String ID 9606.ENSP00000263826
PharmGKB ID PA24686
Target gene [AKT3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004693 chr1 4 5 31 40 View
4011125 chr1 5 2 7 View
4015945 chr1 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of AKT3 expression and immune infiltrating cell level correlation result in HIV+ samples
AKT3 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of AKT3 expression and immune infiltrating cell level correlation result in HIV+ samples
AKT3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).