HTLV1 Target gene Detail Information

> AKR7L Gene Search Result

Gene Information

Gene Name	AKR7L
Gene ID	246181
Gene Full Name	aldo-keto reductase family 7 like (gene/pseudogene)
Gene Alias	AFAR3; AKR7A4; AFB1-AR3; AFB1-AR 3
Virus	HTLV1
Gene Type	protein coding
HGNC ID	HGNC:24056
VEGA ID	OTTHUMG00000002520
OMIM ID	608478
PharmGKB ID	PA164715300

Target gene [AKR7L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002052	chr1	217	35	42	294	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of AKR7L expression and immune infiltrating cell level correlation result in HTLV1+ samples
AKR7L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).