HTLV1 Target gene Detail Information

> AKR7L Gene Search Result


Gene Information
Gene Name AKR7L
Gene ID 246181
Gene Full Name aldo-keto reductase family 7 like (gene/pseudogene)
Gene Alias AFAR3; AKR7A4; AFB1-AR3; AFB1-AR 3
Virus HTLV1
Gene Type protein coding
HGNC ID HGNC:24056
VEGA ID OTTHUMG00000002520
OMIM ID 608478
PharmGKB ID PA164715300
Target gene [AKR7L] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002052 chr1 217 35 42 294 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of AKR7L expression and immune infiltrating cell level correlation result in HTLV1+ samples
AKR7L expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).