HBV Target gene Detail Information

> AKR1A1 Gene Search Result

Gene Information

Gene Name	AKR1A1
Gene ID	10327
Gene Full Name	aldo-keto reductase family 1 member A1
Gene Alias	ALR; ARM; DD3; ALDR1; HEL-S-6
Transcripts	ENSG00000117448
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P14550
HGNC ID	HGNC:380
VEGA ID	OTTHUMG00000007740
OMIM ID	103830
String ID	9606.ENSP00000361140
Drugbank ID	BE0004352
PharmGKB ID	PA24674

Target gene [AKR1A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005709	chr1	47	2		49	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of AKR1A1 expression and immune infiltrating cell level correlation result in HBV+ samples
AKR1A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).